What question did this study set out to answer?

This research aims to compare the effectiveness of proportional assist ventilation (PAV) and pressure support ventilation (PSV) for weaning patients from mechanical ventilation.

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February 13, 2026Open Access

Proportional assist ventilation versus pressure support ventilation for weaning from mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials

Key Points

This research aims to compare the effectiveness of proportional assist ventilation (PAV) and pressure support ventilation (PSV) for weaning patients from mechanical ventilation.
Conducted a systematic review of randomized controlled trials
Compared outcomes between PAV/PAV + and PSV
Analyzed weaning success, mortality, reintubation rates, and duration of mechanical ventilation
No significant difference in weaning success or mortality between PAV and PSV
PAV/PAV + showed a decreased rate of reintubation
Insufficient high-quality evidence prevents strong conclusions

Abstract

We found no significant difference between PAV/PAV + and PSV regarding weaning success, mortality, duration of weaning, or duration of MV. PAV/PAV +, on the other hand, was linked to a decreased rate of reintubation, suggesting a potential benefit in critically ill patients. However, the lack of high-quality evidence precludes any strong conclusions until further large-scale studies confirm these results.

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Proportional assist ventilation versus pressure support ventilation for weaning from mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials

Key Points

Abstract

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