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Influence on sCD40L Value According to ELISA Assay Kits | Synapse

February 13, 2026

Influence on sCD40L Value According to ELISA Assay Kits

Key Points

The study aims to examine how different ELISA kits affect sCD40L reference values and the implications for biomarker reliability.
Comparison of sCD40L values across various ELISA kits
Evaluation of serum versus plasma for sCD40L measurement
Recommendation for institution-specific reference ranges
Significant differences in sCD40L values found between ELISA kits
Serum shows more consistent results than plasma for sCD40L measurement
Standardized reference ranges are crucial for improving biomarker reliability

Abstract

sCD40L reference values differ by ELISA kit, underscoring the need for institution-specific reference ranges. Serum, not plasma, is preferable for sCD40L measurement. Establishing standardized reference ranges will improve the reliability of sCD40L as a biomarker in research fields.

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Cite This Study

Kim et al. (Thu,) studied this question.

synapsesocial.com/papers/698ebf3485a1ff6a93016595 https://doi.org/https://doi.org/10.7754/clin.lab.2025.250551

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