Effectiveness of Ibuprofen Arginine, Ibuprofen Lysine, and Indomethacin for Patent Ductus Arteriosus Closure in Neonates.

Key Points

• The study aims to assess the effectiveness of indomethacin and different ibuprofen formulations for closing patent ductus arteriosus in neonates.
• Evaluated three medications: indomethacin, ibuprofen arginine, ibuprofen lysine.
• Assessed their effects on patent ductus arteriosus closure in neonates.
• All three medications were found to be viable options for pharmacologic closure of PDA.
• Further studies are needed to confirm the findings and improve patient outcomes.