Post-tuberculosis lung disease and pulmonary aspergillosis management: challenges and considerations

Key Points

• The research aims to address the challenges in diagnosing and managing pulmonary aspergillosis in post-tuberculosis lung disease patients.
• Identifying features of chronic pulmonary aspergillosis (CPA) that overlap with tuberculosis (TB)
• Proposing integration of CPA diagnostic bundles into TB programs
• Suggesting standardization of serologic thresholds for diagnosis
• Recommending antifungal stewardship practices
• Developing validated composite response criteria for treatment
• CPA is frequently underdiagnosed due to similarities with TB
• There is a critical need for integrating CPA management into national TB strategies
• Improving serologic testing can enhance diagnostic accuracy and treatment outcomes