KLRG1, KLRC3, and ULK2 are potential biomarkers for predicting MAS in SLE patients. Among them, KLRG1 has the highest sensitivity (0.889) and specificity (0.929) for predicting SLE induced MAS, which is considered the optimal biomarker for diagnosing MAS in SLE. These findings position KLRG1 as a minimally invasive, early-warning biomarker that could promptly predict MAS and might guide timely MAS-directed therapy in SLE.
Pei et al. (Fri,) studied this question.