What question did this study set out to answer?

To highlight the imaging characteristics and diagnosis of succinate dehydrogenase-deficient renal cell carcinoma using 18F-FDG PETCT.

February 19, 2026

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18F-FDG PETCT in a Patient With Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

CWCaixia WuPeking University WDWuning DuWeihai Municipal Hospital XCXueqi ChenChinese Academy of Medical Sciences & Peking Union Medical College

Key Points

To highlight the imaging characteristics and diagnosis of succinate dehydrogenase-deficient renal cell carcinoma using 18F-FDG PETCT.
Examined a 32-year-old male with a renal mass found during a health check-up.
Utilized abdominal enhanced CT to assess the tumor.
Performed 18F-FDG PET/CT for imaging and uptake evaluation.
Conducted radical nephrectomy followed by histopathological and genetic analysis for diagnosis.
The renal tumor showed extremely intense 18F-FDG uptake on PET/CT.
Histopathology confirmed the diagnosis of succinate dehydrogenase-deficient renal cell carcinoma.
Genetic analysis supported the histopathological findings.

Abstract

A 32-year-old man presented with a left renal mass incidentally found during a recent health examination. Renal cell carcinoma was highly suspected by the subsequent abdominal enhanced CT scan. The renal tumor exhibited extremely intense 18 F-FDG uptake on the 18 F-FDG PET/CT. Radical nephrectomy was performed, and the diagnosis of succinate dehydrogenase (SDH)-deficient renal cell carcinoma (SDH-deficient RCC) was confirmed by the histopathology and genetic analysis.

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Cite This Study

Wu et al. (Wed,) studied this question.

synapsesocial.com/papers/6996a7b5ecb39a600b3eda2a https://doi.org/https://doi.org/10.1097/rlu.0000000000006368

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