Surface-Enhanced Stimulated Raman Scattering and Fluorescence Probing of Plasmonic Nanoparticles in Cellular Environments: Insights into the Spatial Distribution and Aggregation

Key Points

• The research aims to explore how nanoparticles are distributed within cells to understand their therapeutic applications.
• Utilized surface-enhanced stimulated Raman scattering and fluorescence techniques.
• Examined the spatial distribution of nanoparticles in cellular environments.
• Assessed aggregation patterns of nanoparticles within cells.
• Showed distinct patterns of intracellular nanoparticle distribution.
• Identified the relationship between nanoparticle aggregation and cellular uptake.
• Indicated potential enhancements in theranostic applications based on intracellular behavior.