Impact Analysis of Community-Led Tuberculosis Treatment Interventions in Rural South African Communities,

Community-led tuberculosis (TB) treatment interventions have been implemented in rural South African communities to improve access to care and adherence. A comprehensive search strategy was employed across multiple databases including PubMed, Cochrane Library, and SA-AIDS, with inclusion criteria based on study design and intervention type. Studies were assessed for methodological quality using the Quality Assessment Tool for Quantitative Studies (QAT-QS). Community-led interventions demonstrated a significant reduction in TB incidence by 25% (95% CI: 18-34%) compared to control groups, with a notable increase in patient adherence rates from baseline. The reviewed studies collectively supported the efficacy of community-led TB treatment programmes, highlighting their potential as sustainable public health solutions in rural settings. Further research should investigate long-term sustainability and scalability of these interventions across different socio-economic contexts. Treatment effect was estimated with logit (pᵢ) =₀+^ Xᵢ, and uncertainty reported using confidence-interval based inference.