Outer-surface charge modulation of photothermal diffusion voltage enables ultrasensitive sensing in nanofluidic membranes

Key Points

• This research aims to enhance the sensitivity of ionic transport through nanofluidic membranes for detecting ultratrace analytes.
• Modulated outer-surface charge of nanofluidic membranes
• Characterized ionic transport dynamics
• Applied photothermal diffusion voltage techniques
• Demonstrated improved sensitivity in detecting ultratrace analytes
• Showed effective regulation of ionic transport
• Quantitative readout improvements over conventional methods