EXPRESS: Research on ambulatory blood pressure characteristics and lifestyle intervention strategies in hypertensive patients based on homocysteine levels

Key Points

• This study aims to explore differences in blood pressure control based on homocysteine levels after lifestyle interventions in hypertensive patients.
• Enrolled 300 hypertensive patients categorized into high and normal homocysteine groups
• Conducted 24-hour ambulatory blood pressure monitoring pre- and post-intervention
• Implemented a standardized 3-month lifestyle intervention including diet and exercise guidance
• The high homocysteine group had significantly higher 24-hour systolic (142.45 mmHg) and diastolic (91.59 mmHg) blood pressure compared to the normal group
• Normal homocysteine group had a higher blood pressure attainment rate (37.33% vs. 19.33%)
• No significant differences in adverse events or adherence rates across groups