What question did this study set out to answer?

To examine the progression of follicular lymphoma from cutaneous to systemic involvement using serial FDG PET/CT.

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February 28, 2026

From Widespread Cutaneous to Systemic Nodal Involvement: Serial FDG PET/CT Findings in Follicular Lymphoma

Key Points

To examine the progression of follicular lymphoma from cutaneous to systemic involvement using serial FDG PET/CT.
Initial evaluation with 18F-FDG PET/CT to assess cutaneous and subcutaneous involvement.
Follow-up PET/CT post-therapy to evaluate treatment response and progression.
Assessment of lymphadenopathy using imaging techniques.
Initial scan showed extensive cutaneous and subcutaneous uptake.
Post-therapy follow-up revealed new widespread hypermetabolic lymph nodes.
Indicated potential systemic progression despite resolution in skin uptake.

Abstract

A 57-year-old woman with follicular lymphoma (FL) presented with diffuse cutaneous and subcutaneous involvement on baseline 18F-FDG PET/CT. Following therapy, cutaneous uptake largely resolved; however, follow-up PET/CT demonstrated new, widespread confluent hypermetabolic lymphadenopathy, indicating systemic progression. This striking post-therapy redistribution highlights the importance of serial whole-body PET/CT in atypical FL.

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From Widespread Cutaneous to Systemic Nodal Involvement: Serial FDG PET/CT Findings in Follicular Lymphoma

Key Points

Abstract

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