Left atrial resection surgery for NSCLC achieved a median overall survival of 2.11 years, with complete resection yielding a significantly longer median survival of 3.12 years versus 0.64 years for incomplete resection (p=0.01).
Observational (n=41)
No
What are the surgical outcomes and predictors of long-term survival in patients undergoing left atrial resection for non-small cell lung cancer with left atrial invasion?
In selected patients with NSCLC invading the left atrium, surgical resection is feasible and can provide long-term survival, particularly when complete (R0) resection is achieved and N2 nodal disease is absent.
In NSCLC with left atrial invasion, surgery is feasible in selected patients, and long-term survival depends on excluding N2 disease and achieving complete resection.
Kosif et al. (Fri,) conducted a observational in Patients with non-small cell lung cancer invading the left atrium without distant or pleural/pericardial metastasis, limited mediastinal nodal involvement without bulky N2 or N3 disease, preserved cardiac function (LVEF >50%, no severe valve disease or pulmonary hypertension), and sufficient cardiopulmonary reserve (predicted postoperative FEV1 >40%) (n=41). Left atrial resection with lung resection (pneumonectomy, bilobectomy or lobectomy) was evaluated on Overall survival (time from surgery to death from any cause) (95% CI Median OS 2.11 years (95% CI, 1.17-3.05)). Left atrial resection surgery for NSCLC achieved a median overall survival of 2.11 years, with complete resection yielding a significantly longer median survival of 3.12 years versus 0.64 years for incomplete resection (p=0.01).