High accuracy in detecting HER2-low status in FNA of primary and metastatic breast cancer. | Synapse
March 1, 2026
High accuracy in detecting HER2-low status in FNA of primary and metastatic breast cancer.
Key Points
The aim is to assess the reliability of FNAC-derived cell blocks in identifying HER2-low breast carcinomas.
Utilized fine needle aspiration cytology (FNAC)
Evaluated cell blocks (CBs) from primary and metastatic breast cancer
Compared results to traditional histological samples
Identified HER2-low status accurately when histological samples were limited
Emphasized need for standardized evaluation criteria
Demonstrated reliability of FNAC-derived CBs
Abstract
FNAC-derived CBs are a reliable tool for identifying HER2-low breast carcinomas when histological samples are unavailable or limited, emphasizing the need for standardized evaluation criteria.