Preoperative Tranexamic Acid Use in Free Flap Breast Reconstruction: A Propensity-Matched Analysis of Postoperative Outcomes. | Synapse
March 1, 2026
Preoperative Tranexamic Acid Use in Free Flap Breast Reconstruction: A Propensity-Matched Analysis of Postoperative Outcomes.
Key Points
To evaluate the impact of preoperative tranexamic acid (TXA) use on postoperative outcomes in free flap breast reconstruction.
Conducted a propensity-matched analysis of patients undergoing breast reconstruction.
Compared outcomes in those receiving TXA versus those who did not.
Evaluated the incidence of hematoma and other complications postoperatively.
TXA use was linked to a higher occurrence of hematoma post-surgery.
No significant reduction in the rate of other complications was observed.
Abstract
Contrary to prior reports, preoperative TXA use in free flap breast reconstruction was associated with a higher incidence of hematoma, without significant reduction in the rate of other complications.