Impact of genetic diversity of PCSK9 polymorphisms on coronary artery disease in a sample of Iraqi individuals.

Key Points

• The study aims to explore the relationship between PCSK9 polymorphisms and coronary artery disease (CAD) risk in Iraqi individuals.
• Analyzed genetic diversity of PCSK9 polymorphisms in a sample of Iraqi individuals.
• Investigated the association of rs2479394 G/A genotype and T-A haplotype with CAD risk.
• Measured serum PCSK9 levels and assessed dyslipidemia in CAD patients.
• The rs2479394 G/A genotype and T-A haplotype are linked to lower risk of CAD.
• Elevated serum PCSK9 levels and dyslipidemia were present in CAD patients.
• No correlation was found between rs2479394 and measured dyslipidemia traits.