Anti-CD146 Autoantibodies: The First Biologic Markers Associated With Occupational Exposure in Systemic Sclerosis.

Key Points

• The aim is to investigate the presence of anti-CD146 autoantibodies in relation to occupational dust exposure in systemic sclerosis.
• Conducted an analysis of patients with systemic sclerosis (SSc).
• Examined the association between autoantibodies and occupational dust exposure.
• Identified biomarkers linked to male workers.
• Anti-CD146 autoantibodies were detected in patients with systemic sclerosis.
• These autoantibodies were specifically linked to male workers exposed to occupational dust.
• First identification of biomarkers associated with occupational exposure in systemic sclerosis.