Assessment of LDL receptor-dependent lipid lowering therapies in patients with homozygous familial hypercholesterolemia according to functional genotype
Key Points
LDL receptor-dependent therapies effectively lower lipid levels in patients.
Cholesterol levels decreased markedly, with specific attention to genotype functionality.
Observational analysis focused on patients with homozygous familial hypercholesterolemia and their genotypes.
These results highlight the importance of functional genotype in therapy responsiveness.
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Assessment of LDL receptor-dependent lipid lowering therapies in patients with homozygous familial hypercholesterolemia according to functional genotype | Synapse