Low-temperature plasma-activated Ringer’s lactate solution induces apoptosis in melanoma cells by downregulating heat shock proteins and by inducing mitochondrial dysfunction

Key Points

• Apoptosis is induced in melanoma cells by plasma-activated Ringer's lactate, highlighting its potential therapeutic role.
• A key finding shows downregulation of heat shock proteins and mitochondrial dysfunction in the treated melanoma cells.
• This analysis examines the effects of plasma-activated Ringer’s lactate on melanoma cell lines under controlled conditions.
• The findings suggest this approach could represent a novel treatment for malignant melanoma, with promising implications.