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BmTrpA1-Mediated ILP/AKT/FOXO signaling Underlies Temperature-Dependent diapause in Silkworms, Bombyx mori | Synapse
March 3, 2026
BmTrpA1-Mediated ILP/AKT/FOXO signaling Underlies Temperature-Dependent diapause in Silkworms, Bombyx mori
ZY
Zhang Yizhong
HS
Haoping She
Jiangsu University of Science and Technology
WS
Wang Shanshan
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Key Points
Diapause regulation correlates with BmTrpA1 function, influencing larval development and survival.
Key metrics show significant changes in ILP, AKT, and FOXO proteins under temperature variations.
Using gene expression analysis, this observational assessment links temperature to signaling pathways in silkworms.
Findings suggest that manipulating these pathways may improve silkworm cultivation and resilience against climate changes.
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Yizhong et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75a07c6e9836116a1f820
https://doi.org/https://doi.org/10.1016/j.jinsphys.2026.104939