MiR-874-3p suppresses TNF-α-induced inflammation in adipocytes by targeting nucleolin

Key Points

• Mir-874-3p significantly reduces inflammation induced by TNF-α, highlighting its potential therapeutic role.
• Inhibition of TNF-α-induced inflammation was observed, with a notable reduction in inflammatory markers.
• The study utilized adipocytes to assess the impact of miR-874-3p on inflammation pathways involving nucleolin.
• Findings suggest that targeting miR-874-3p could provide a new strategy for managing obesity-related inflammation.