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Synthesis and nucleophilic dearomatization of novel 1,2,4triazolo1,5-apyrimidines | Synapse
March 3, 2026
Synthesis and nucleophilic dearomatization of novel 1,2,4triazolo1,5-apyrimidines
SK
S. A. Kolyadina
AK
A. A. Kruchinin
MM
Mikhail E. Minyaev
N.D. Zelinsky Institute of Organic Chemistry
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Key Points
The nucleophilic dearomatization process yields novel triazolo-pyrimidines, enhancing synthetic utility.
A new reaction pathway is established through this synthesis, highlighting innovative chemical strategies.
Synthesis involves strategic manipulation of chemical bonds, with implications for pharmacological applications.
The results suggest potential for developing new compounds in medicinal chemistry, with further studies warranted.
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Kolyadina et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75a26c6e9836116a1fb60
https://doi.org/https://doi.org/10.1016/j.tet.2026.135153
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