Intrinsic connectivity patterns of striatal subfields predict individual dimensions of psychopathology and are associated with cholinergic and serotonergic neurotransmission in schizophrenia | Synapse
March 3, 2026
Intrinsic connectivity patterns of striatal subfields predict individual dimensions of psychopathology and are associated with cholinergic and serotonergic neurotransmission in schizophrenia
Key Points
Intrinsic connectivity patterns predict individual dimensions of psychopathology in schizophrenia, highlighting their potential role in mental health outcomes.
Cholinergic and serotonergic neurotransmission are significantly associated with these connectivity patterns, suggesting a biochemical link to psychopathology.
This analysis utilized brain imaging techniques to explore connectivity in specific striatal subfields, focusing on their relevance to clinical symptoms.
Findings may enable targeted interventions by enhancing the understanding of specific neurotransmitter roles in schizophrenia.