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Deciphering stromal cell interactions in osteosarcoma highlights CDKN2A and MMP14 as novel diagnostic and therapeutic biomarkers | Synapse
March 3, 2026
Open Access
Deciphering stromal cell interactions in osteosarcoma highlights CDKN2A and MMP14 as novel diagnostic and therapeutic biomarkers
XP
Xiwen Peng
HJ
Haobo Jiang
YS
Yicheng Sun
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Key Points
Stromal cell interactions reveal CDKN2A and MMP14 as potential biomarkers for osteosarcoma, enhancing diagnostic capabilities.
The analysis identifies specific cellular interactions, showing the significance of these biomarkers in cancer pathology.
Assessment of stromal cells and their role in tumor microenvironments underscores the importance of targeted therapies.
Identifying CDKN2A and MMP14 could lead to novel treatment strategies, requiring further validation in clinical settings.
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Peng et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a74c6e9836116a204a9
https://doi.org/https://doi.org/10.1186/s40001-026-03902-2
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