Awake surgery versus general anesthesia in the treatment of Diffuse Low-Grade Gliomas – and the role of supplementary intraoperative techniques: a systematic review and meta-analysis

Key Points

• Awake surgery enhances the preservation of neurological function in patients with diffuse low-grade gliomas, improving outcomes.
• Reports indicate significant functional outcomes, with awake surgery showing advantages over traditional anesthesia in specific cases.
• Systematic review and meta-analysis assessed 32 studies focusing on intraoperative techniques and their efficacy.
• Findings may enable personalized approaches to glioma surgery, optimizing interventions according to patient needs.