lncRNA SND1-IT1/miR-494-3p regulation in ox-LDL-induced endothelial cell injury: novel insights into coronary heart disease pathogenesis and diagnostic biomarkers

Key Points

• Altered expression of lncRNA SND1-IT1 and miR-494-3p associates with coronary heart disease risk.
• The regulation of ox-LDL-induced endothelial cell injury involves the interaction between miR-494-3p and ZBTB20.
• Analysis involved endothelial cells exposed to ox-LDL to mimic conditions in coronary heart disease.
• These findings suggest novel biomarkers for assessing coronary heart disease and its pathogenesis.