The Content of Dietary Melatonin in 119 Food Items and Its Relationship With Chronic Diseases: Results of the CUME+ Study

Key Points

• Dietary melatonin intake shows an inverse relationship with obesity and depression, suggesting it may have protective effects.
• The strongest connection noted is a non-linear dose-response pattern for depression, highlighting potential nuances.
• Longitudinal and experimental studies are necessary to confirm these initial observations in chronic disease contexts.
• Further investigation is crucial to understand the underlying mechanisms linking dietary melatonin with health outcomes.