Correlation of miR-214, miR-204, miR-25, miR-15a Expression with IL-33 and Malondialdehyde in Blood Samples from Patients with Alzheimer’s Disease | Synapse
March 3, 2026
Correlation of miR-214, miR-204, miR-25, miR-15a Expression with IL-33 and Malondialdehyde in Blood Samples from Patients with Alzheimer’s Disease
Key Points
Expression levels of specific miRNAs and IL-33 correlate with malondialdehyde in Alzheimer's disease samples, offering new insights into biomarker status.
Elevated miR-214, miR-204, miR-25, and miR-15a correlate with increased IL-33 and malondialdehyde, potentially indicating disease progression.
Study analyzes plasma samples for biomarkers relevant to Alzheimer’s disease, revealing significant findings related to oxidative stress.
Findings support ongoing efforts to identify reliable biomarkers for early diagnosis and tracking of Alzheimer’s disease.
Abstract
Expression levels of the studied miRNAs and IL33, and plasma level of MDA might be considered as potential biomarkers for AD development and diagnosis.