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The role of allopurinol in metabolic dysfunction-associated steatotic liver disease: A randomized clinical trial | Synapse
March 3, 2026
The role of allopurinol in metabolic dysfunction-associated steatotic liver disease: A randomized clinical trial
EK
Elnaz Khani
MK
Manouchehr Khoshbaten
MJ
Mohammad Asghari Jafarabadi
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Key Points
Allopurinol treatment is linked to improvements in liver enzymes, indicating potential benefits for steatotic liver disease.
Participants receiving allopurinol showed a significant reduction in oxidative stress markers after treatment.
Randomized clinical trial methodology allows robust evaluation of allopurinol's efficacy in this patient population.
These findings support potential therapeutic strategies for managing metabolic dysfunction-related liver conditions.
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Khani et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75adcc6e9836116a213d3
https://doi.org/https://doi.org/10.1016/j.ajg.2025.11.004
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