Toxicity profiles of proton and photon radiotherapy in postoperative breast cancer: a 10-year real-world cohort study

Key Points

• Proton radiotherapy has distinct toxicity profiles compared to photon radiotherapy, particularly in long-term outcomes.
• In the cohort of postoperative breast cancer patients, proton therapy resulted in fewer adverse effects over 10 years than photon therapy.
• Observational analysis across a decade evaluates treatment efficacy and safety, revealing critical insights into patient care.
• Findings support further investigation into personalized radiation therapy strategies for improved patient management.