Interstitial lung disease in systemic autoimmune rheumatic diseases: radiologic and histologic correlations

Key Points

SSc-ILD and RA-ILD show fair-to-moderate correlation between histology and HRCT imaging patterns, indicating limitations in diagnosis.
IIM-ILD displays significant histologic heterogeneity, suggesting stricter analysis may be required for accurate pathology assessment.
Anti-MDA5+ disease exhibits aggressive progression, highlighting challenges in predicting outcomes based solely on imaging findings.
Assessment of interstitial lung disease across various systemic autoimmune rheumatic diseases reveals complex correlations.

Abstract

SSc-ILD and RA-ILD demonstrated fair-to-moderate HRCT-histology correlation, whereas IIM-ILD shows marked histologic heterogeneity independent of imaging patterns. Anti-MDA5+ disease consistently exhibited aggressive progression, underscoring the limitations of HRCT in predicting IIM-ILD pathology.

Interstitial lung disease in systemic autoimmune rheumatic diseases: radiologic and histologic correlations

Key Points

Abstract

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