Structure and mechanism of the human bile acid transporter OSTα–OSTβ

Key Points

• The OSTα–OSTβ transporter facilitates bile acid transport across cell membranes, enhancing metabolism.
• Key structural features were identified, revealing how the transporter interacts with bile acids.
• Analysis involved advanced imaging techniques to elucidate the transporter's function at the molecular level.
• Understanding this mechanism supports potential therapeutic targets for metabolic disorders involving bile acids.