Structure-based screening of marine carotenoids: fucoxanthin and its derivatives as potential inhibitors of the SARS-CoV-2 nucleocapsid phosphoprotein | Synapse
March 3, 2026Open Access
Structure-based screening of marine carotenoids: fucoxanthin and its derivatives as potential inhibitors of the SARS-CoV-2 nucleocapsid phosphoprotein
Key Points
Fucoxanthin demonstrates potential as an inhibitor of SARS-CoV-2 nucleocapsid phosphoprotein, indicating promise in antiviral applications.
Key metric shows significant interaction against the nucleocapsid phosphoprotein in testing scenarios, likely aiding COVID-19 management.
Structure-based screening analysis identified marine carotenoid derivatives that may reduce viral activity and replication.
Findings highlight the need for further exploration of marine-derived compounds in pathogen inhibition, emphasizing the role of nature in drug discovery.