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March 3, 2026
Open Access
Gut-brain axis in Attention Deficit Hyperactivity Disorder (ADHD): A narrative review of the links between gut microbiota and ADHD pathophysiology
BL
Barbara Luyens
FF
Francisco Felgueroso-Bueno
AE
Amandine Everard
Walloon Excellence in Lifesciences and Biotechnology
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Key Points
ADHD is linked to variations in gut microbiota composition, indicating possible connections to disease mechanisms.
Notably, alterations in bacterial diversity may influence neurotransmitter levels in individuals with ADHD.
Narrative review examined existing literature on gut-brain interactions related to ADHD pathology and gut health.
Findings suggest underlying biological pathways in ADHD could be modulated by gut microbiota, highlighting new therapeutic avenues.
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Gut-brain axis in Attention Deficit Hyperactivity Disorder (ADHD): A narrative review of the links between gut microbiota and ADHD pathophysiology | Synapse
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Luyens et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c4ec6e9836116a250f3
https://doi.org/https://doi.org/10.1016/j.jpsychires.2026.01.038