Impact of mismatch repair genes deficiency on survival outcomes and establishment of a novel prognostic prediction model for stage I-II endometrial carcinoma

Key Points

• Early-stage endometrial carcinoma patients with mismatch repair deficiency experience poorer survival outcomes.
• The study indicates that combining MMR status with clinicopathological factors can create a novel prognostic prediction model.
• Full molecular sequencing is recommended to determine the prognostic significance of MMR status in patients.
• Further prospective research is needed to validate the findings and refine the prognostic model.