Identification of the Novel HLA‐DPA1*02:02:21 Allele by PolyseqOne and Oxford Nanopore Sequencing

Key Points

• HLA-DPA1*02:02:21 differs from the HLA-DPA1*02:02:02 allele by a single nucleotide substitution in exon 2.
• The identification highlights the importance of thorough genetic sequencing in understanding human genetic diversity.
• PolyseqOne and Oxford Nanopore sequencing techniques were employed to uncover this novel allele variant.
• This discovery may enhance future genetic studies and personalized medicine approaches, requiring further exploration.