Development of selective NBD-based fluorescent probes for in vitro detection of factor XIa and Thrombus imaging

Key Points

• These novel fluorescent probes specifically target factor XIa, enhancing detection capabilities within thrombus imaging.
• The probes improved sensitivity, allowing detection at lower concentrations of factor XIa compared to previous methods.
• Observational analysis of in vitro detection methods demonstrates the effectiveness of the NBD-based probes for thrombus imaging applications.
• This development supports more accurate thrombus diagnosis, indicating potential clinical benefits in thrombotic disorder management.