The role of Quad Shot in palliative radiotherapy: narrative review of the evidence and applications in advanced head and neck cancer

Key Points

• Palliative radiotherapy using the Quad Shot regimen improves patient comfort and pain relief.
• The regimen is particularly effective for patients with advanced head and neck cancer and comorbid conditions.
• Assessment of ongoing studies will evaluate the integration of Quad Shot with systemic therapies.
• Findings suggest that the Quad Shot approach may enable better treatment planning for advanced cancer cases.