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Lanatoside C ameliorates DSS-induced colitis with improved intestinal barrier integrity and reduced M1 macrophage polarization | Synapse
March 3, 2026
Open Access
Lanatoside C ameliorates DSS-induced colitis with improved intestinal barrier integrity and reduced M1 macrophage polarization
LY
Longmei Yu
Beijing University of Chinese Medicine
JL
Juntong Liu
Beijing University of Chinese Medicine
XZ
Xinyu Zhao
South China Agricultural University
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Key Points
Lanatoside C ameliorates DSS-induced colitis, enhancing gut health and barrier function.
The treatment notably reduced M1 macrophage polarization, which is linked to inflammation.
Analysis focused on changes in intestinal barrier integrity and inflammatory responses in a colitis model.
These findings support the potential role of lanatoside C in treating inflammatory bowel disease.
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Yu et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d3ac6e9836116a26e4f
https://doi.org/https://doi.org/10.1038/s41598-026-37484-0