A highly efficient HA-targeted smart pH-responsive liposomal synergistic delivery system for TLR7/8 receptor agonist Imiquimod/methyl pyropheophorbide a-copper: Experimental study on remodeling the immune microenvironment of cold tumors and inhibiting tumor metastasis | Synapse
March 3, 2026
A highly efficient HA-targeted smart pH-responsive liposomal synergistic delivery system for TLR7/8 receptor agonist Imiquimod/methyl pyropheophorbide a-copper: Experimental study on remodeling the immune microenvironment of cold tumors and inhibiting tumor metastasis
Key Points
Targeted delivery system remodels the immune microenvironment and inhibits tumor metastasis.
Key findings include a significant reduction in metastasis rates in cold tumor models.
Experimental study employs a liposomal delivery system with pH-responsive properties to improve drug efficacy.
These findings may suggest new therapeutic strategies for enhancing immune response in tumor treatment.