Encapsulated Papillary Carcinoma of the Breast: Two Cases with Literature Review and Molecular Insights.

Key Points

Encapsulated papillary carcinoma shares genetic features with invasive ductal carcinoma, indicating similar underlying pathways.
Common mutations in the PIK3CA gene were identified, emphasizing the relevance of molecular insights in diagnosis.
Histopathological and immunohistochemical analyses confirmed the encapsulated papillary carcinoma diagnosis in both cases.
Integration of clinical, histological, and molecular findings enhances understanding for better management strategies.

Abstract

Histopathological and immunohistochemical analyses confirmed the EPC diagnosis, and molecular insights revealed common mutations, particularly in the PIK3CA gene. This report underscores the importance of integrating clinical, histological, and molecular findings to guide diagnosis and management of EPC, which, despite its low invasive potential, shares genetic features with invasive ductal carcinoma.

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Encapsulated Papillary Carcinoma of the Breast: Two Cases with Literature Review and Molecular Insights.

Key Points

Abstract

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