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Investigating the epigenetic modulating potential of gallic acid during ethanol-induced toxicity: In silico and in vitro approaches | Synapse
March 3, 2026
Investigating the epigenetic modulating potential of gallic acid during ethanol-induced toxicity: In silico and in vitro approaches
RA
R. Armstrong
KN
Krithika Narayanan
MN
Maheshvare Natesan
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Key Points
Gallic acid significantly decreases ethanol-induced oxidative stress in cell cultures, enhancing cellular viability.
The study observed a reduction in key biomarkers linked to ethanol toxicity following gallic acid treatment over a specific duration.
Assessment using in vitro methods demonstrated that gallic acid modulates epigenetic factors impacted by ethanol exposure.
These findings indicate potential therapeutic applications but require further exploration of epigenetic mechanisms.
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Armstrong et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75dd5c6e9836116a28169
https://doi.org/https://doi.org/10.1016/j.bioorg.2026.109576