Comparative effectiveness and safety of novel antidiabetic agents in the management of obstructive sleep apnea: a systematic review, meta-analysis, and network meta-analysis

Key Points

• Antidiabetic agents show varying effectiveness in managing obstructive sleep apnea outcomes and associated symptoms, highlighting treatment selection importance.
• The analysis revealed significant differences in effectiveness—certain agents improved apnea severity more than others in various patient populations.
• Utilizing systematic review and meta-analysis methods, the study compared multiple antidiabetic agents to evaluate their impacts on sleep apnea.
• These findings support potential implications for adjusting diabetes treatment strategies, particularly in patients with sleep apnea.