PCMTD1-127aa suppresses osteosarcoma progression by competitively binding to USP10 to promote c-MYC degradation

Key Points

• PCMTD1-127aa reduces osteosarcoma progression, indicating its role in tumor suppression.
• Key evidence shows a significant reduction in c-MYC levels associated with PCMTD1-127aa interaction with USP10.
• Analysis of protein interactions reveals that PCMTD1-127aa competes with USP10, enhancing c-MYC degradation.
• Findings may enable new therapeutic strategies targeting protein interactions in osteosarcoma.