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KDM5D epigenetically represses FERD3L to inhibit tumor growth in male colorectal cancer | Synapse
March 3, 2026
KDM5D epigenetically represses FERD3L to inhibit tumor growth in male colorectal cancer
JY
Jianwei Yu
XZ
Xuejing Zhong
QL
Qinfen Lan
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Key Points
Tumor growth is inhibited by KDM5D through the repression of FERD3L, indicating its role in colorectal cancer.
The analysis shows a significant relationship between KDM5D levels and tumor progression metrics in males.
Observational analysis across different male colorectal cancer samples highlights the epigenetic role of KDM5D.
Findings suggest KDM5D may be a valuable therapeutic target, requiring further exploration in male-specific colorectal cancer.
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Yu et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75e98c6e9836116a2959c
https://doi.org/https://doi.org/10.1016/j.cellsig.2026.112402