Evaluation of PACAP-38 and CGRP levels in restless legs syndrome

Key Points

• PACAP-38 and CGRP levels were significantly altered in restless legs syndrome patients, suggesting their role as biomarkers.
• The study observed 45 patients with restless legs syndrome and found notable differences in biomarker levels.
• This observational analysis utilized laboratory assessments to determine PACAP-38 and CGRP levels related to symptoms.
• Understanding these biomarker changes may enhance diagnostic strategies and treatment options for restless legs syndrome.