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Biocatalytic synthesis of fluorine-containing chiral azido compounds in a two-phase system | Synapse
March 3, 2026
Biocatalytic synthesis of fluorine-containing chiral azido compounds in a two-phase system
RK
Robert Junior Kolman
NM
Nevena Milčić
IA
Ivana Leščić Ašler
Rudjer Boskovic Institute
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Key Points
The synthesis of chiral azido compounds was efficiently achieved using biocatalysis in a two-phase system.
Yield improvements in fluorine-containing compounds were noted during the synthesis process, with notable purity levels.
Analysis employed a two-phase system to facilitate the biocatalytic reactions, enhancing the overall efficiency of the process.
These findings highlight potential advancements in creating complex fluorinated compounds, though scalability needs evaluation.
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Kolman et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75ec5c6e9836116a29ae9
https://doi.org/https://doi.org/10.1016/j.tetlet.2026.155982
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