Posterior reversible encephalopathy syndrome in sickle cell disease: A tale of two cases with distinct etiologies

Key Points

• Neurological symptoms consistent with posterior reversible encephalopathy syndrome were observed in both cases.
• One patient experienced acute hypertension alongside their symptoms, while the other had a different underlying cause.
• Clinical evaluation revealed distinct etiologies contributing to the syndrome in sickle cell disease, impacting treatment options.
• These findings highlight the importance of identifying unique causes within this patient population for effective management.