Kappa free light chains as a reliable alternative to oligoclonal bands in Korean MS patients: Diagnostic accuracy and sex-specific insights

Key Points

• Kappa free light chains showed a diagnostic accuracy rate exceeding 85% in Korean multiple sclerosis patients.
• The analysis also revealed notable sex-specific differences affecting diagnostic outcomes in this population.
• Using kappa free light chains could enhance the diagnostic toolkit for multiple sclerosis compared to traditional oligoclonal bands.
• Diagnostic techniques must consider both sex-specific indicators and the use of newer biomarkers for optimal efficacy.