Nutrigenomic influence of a curcumin-supplemented high glycemic diet on hippocampal microvasculature in male C57BL/6J mice

Key Points

• Curcumin induces notable nutrigenomic modifications that protect the hippocampal microvasculature.
• This neuroprotective effect occurs in the context of a high glycemic diet, which typically causes dysfunction.
• The study emphasizes the relevance of diet and nutrigenomics in neurological health and disease prevention.
• Findings suggest that dietary interventions could play a crucial role in maintaining cognitive functions, highlighting curcumin's potential.