Outcomes after Bone Marrow Versus Peripheral Blood Matched Unrelated Donor Hematopoietic Cell Transplantation Using Posttransplant Cyclophosphamide-Based GVHD Prophylaxis

Key Points

• Outcomes indicate that bone marrow transplantation leads to lower rates of graft-versus-host disease (GVHD) compared to peripheral blood transplantation.
• Recent findings suggest a significant reduction of GVHD incidences by 30% when using posttransplant cyclophosphamide-based prophylaxis.
• Observational analysis across multiple medical centers compared the efficacy and safety of donor sources in hematopoietic cell transplantation.
• This data highlights the importance of donor type in improving post-transplant outcomes, implying a need for further studies in diverse populations.